Search results for "diazonium salts"

showing 5 items of 5 documents

An insight into the functionalisation of carbon nanotubes by diazonium chemistry: Towards a controlled decoration

2014

The derivatisation of materials including iron, gold, and carbon by addition of diazonium salts is a reliable process to tune their interfacial interaction with the surrounding media. In this regard, the functionalisation of carbon nanostructures by diazonium chemistry is a versatile strategy to obtain soluble nanomaterials with degrees of functionalisation among the highest ever reported. Starting from these premises we have studied the functionalisation of multi-walled carbon nanotubes by addition of the aryl diazonium salts generated in situ by treatment of 4-methoxyaniline with isopentylnitrite. Following a thorough purification and characterisation protocol (UV-vis, TGA, ATR-IR, cyclic…

Materials scienceArylSelective chemistry of single-walled nanotubeschemistry.chemical_elementNanotechnologyCarbon Nanotubes diazonium salts functionalisation of carbon nanostructures decorated carbon nanostructuresGeneral ChemistryCarbon nanotubeengineering.materialNanomaterialslaw.inventionchemistry.chemical_compoundchemistryCoatingCarbon Nanotubes Functionalisation . Diazonium chemistrylawMonolayerengineeringGeneral Materials ScienceCyclic voltammetryCarbonCarbon
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Modulation of the organic heterojunction behavior, from electrografting to enhanced sensing properties

2019

International audience; The energy barrier of an organic heterojunction built on ITO electrodes and made from a low conductive sublayer (Cu(F16Pc)) covered by a highly conductive semiconductor (LuPc2) is modulated by electrografting of organic layers before depositing the sublayer. Impedance spectroscopy clearly demonstrates the increase of the energy barrier at the ITO – sublayer interface. Additionally, the electrografting is a versatile and promising method for the tuning of heterojunctions. The I(V) characteristics of the heterojunctions are highly modified by the electrografting. The same electromodifications of electrodes carried out on LuPc2 resistors lead to a modification of their …

Materials scienceImpedance spectroscopy02 engineering and technology010402 general chemistry01 natural scienceslaw.invention[CHIM.ANAL]Chemical Sciences/Analytical chemistrylawMaterials ChemistryElectrical and Electronic EngineeringInstrumentationElectrical conductorDetection limitOrganic electronicsOrganic electronicsbusiness.industryMetals and AlloysHeterojunction021001 nanoscience & nanotechnologyCondensed Matter PhysicsDiazonium saltsAmmonia sensors[SPI.TRON]Engineering Sciences [physics]/Electronics0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsDielectric spectroscopyMolecular materialsSemiconductorElectrodeOptoelectronicsResistor[CHIM.OTHE]Chemical Sciences/Other0210 nano-technologybusinessSensors and Actuators B: Chemical
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Radical Cyclization and 1,5-Hydrogen Transfer in Selected Aromatic Diazonium Salts

2014

2-(Methyl(3-methyl-1-phenyl-1H-pyrazol-5-yl)carbamoyl)thiophene-3-diazonium hydrogen sulfate 20, 2-(methyl(3-methyl-isoxazol-5yl)carbamoyl)-benzenediazonium hydrogen sulfate 21 and 2-(methyl(phenyl)carbamoyl)-benzenediazonium hydrogen sulphate 22 were synthesized and reacted with a CuSO4/NaCl/ascorbic acid combination to give complex mixtures. The structures of the reaction products were elucidated, depending upon the pathways followed. Compound 20 almost exclusively afforded an Ar-5 cyclization product and trace amounts of the product derived from a competing Ar-6 Pschorr closure. In the case of compound 21, the Ar-6 cyclization was not observed, while the Ar-5 cyclization and 1,5-hydrogen…

PharmacologyRadical-nucleophilic aromatic substitutionChemistryOrganic ChemistryOrganic chemistryHydrogen transferSettore CHIM/06 - Chimica OrganicaSettore CHIM/08 - Chimica FarmaceuticaRadical cyclizationRadical cyclizations. 15-hydrogen transfer. Diazonium salts. Isoxazole. Thiophene.Settore CHIM/02 - Chimica FisicaAnalytical ChemistryHETEROCYCLES
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Unravelling Radicals Reactivity Towards Carbon Nanotubes Manipulation/Functionalization

2016

Carbon Nanotubes (CNTs) chemistry is under constant evolution, as a consequence of the deep interest of the scientific community in finding new applications for these versatile materials. New and old synthetic protocols are used for improving the control of the functionalization degree of the final materials and for offering to scientists the possibility to fine-tune their final properties. In this Review, we focus the attention on radical reactions, a class of protocols characterized by small number of steps, different degrees of functionalization and enhanced solubility of the final modified CNTs, in the desired environment. The most well-known protocols are analysed providing some releva…

Radical02 engineering and technologyCarbon nanotube010402 general chemistryPhotochemistry01 natural sciencesCarbon nanotubelaw.inventioncarboxylationBirch reductionlawepoxidationOrganic chemistryReactivity (chemistry)diazonium saltsradicalBirch reductionChemistryOrganic Chemistry021001 nanoscience & nanotechnologyradicals0104 chemical sciencesCarboxylationdiazonium saltSurface modificationCarbon Nanotubespolymer grafting0210 nano-technologyCarbon Nanotubes radicals carboxylation diazonium salts Birch reduction epoxidation polymer grafting
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Rational Chemical Multifunctionalization of Graphene Interface Enhances Targeted Cancer Therapy

2020

The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer activity. The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal properties prove the great advantage of a combined chemo‐ and phototherapy based on graphene against cancer, opening the doors to future therapeutic applications of this type of material.

multifunctionalizationCarbon materialsCancer therapyAntineoplastic AgentsNanotechnology[CHIM.THER]Chemical Sciences/Medicinal Chemistry010402 general chemistry01 natural sciencesCatalysislaw.inventionDrug Delivery SystemslawCell Line TumorNeoplasmsmedicineHumanscancerDoxorubicindiazonium saltsCàncerMaterialsComputingMilieux_MISCELLANEOUSgraphite010405 organic chemistryGrapheneChemistryCancerGeneral MedicineGeneral ChemistryPhotothermal therapymedicine.disease0104 chemical sciencesDrug deliveryCancer cellSurface modificationmedicine.drugAngewandte Chemie International Edition
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